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An article published on The American Journal on Addictions stated that women that are pregnant who were dependent on opioids were strongly interested in antagonist treatment, especially the one which involves the use of naltrexone to combat their abusing drugs disorder. Using two separate drugs to lose weight can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err on the side of caution and permit the FDA do its job and demand some research be done so your public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on his or her medications. Researchers found out that participants investing in this drug for a year, lost excess weight within 4 weeks and have kept the load off throughout the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more efficient and safer. Combo-pilling may be the newest fad or also the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular is the fact that at the time of right now there aren't long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure level and heart rate, and really should not be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high blood pressure level, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stopping smoking. Other people who must avoid using Contrave are patients experiencing bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave mustn't be prescribed for ladies who are pregnant or attempting to become pregnant.